Identiftying critical points of failure within the health system and during emergencies is the first step to mitigating future risk exposure. The West African Ebola epidemic (2014-2016) revealed alarming gaps in infection prevention and control for health care workers, highlighting a major vulnerability in global health security. Experts from Resolve to Save Lives propose a two-pronged soluion: prioritizing IPC as a global epidemic preparedness measure and conducting rapid risk assessments to adapt strategies for health care worker protection. Improved global support and targeted interventions are vital to strengthen health systems and safeguard frontline workers.